Established from an ascites of a tumour induced in a male mouse by intraperitoneal injection of Abelson Leukaemia Virus (A-MuLV). Cells will pinocytose neutral red and phagocytose zymosan. Cells capable of antibody dependent lysis of sheep erythrocytes and tumour targets. Growth inhibited by LPS.
The ISRE Reporter kit is designed for monitoring the activity of Type I interferon-induced JAK/STAT signaling pathway in the cultured cells.
|Stability:||32 passages(in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Freeze Medium:||90% FBS+10% DMSO|
|Culture Medium:||DMEM+10%FBS+200ug/ml zeocin|
|IV. Description of Host Cell Line|
|Organism:||Mus musculus, mouse|
|Tissue:||Abelson murine leukemia virus-induced tumor; ascites|
|Disease:||Abelson murine leukemia virus-induced tumor|
|Ⅴ. Representative Data|
Figure 1. Dose Response of 2'3-cGAMP in RAW264.7 ISRE-Luc Cells , the EC50 was 8.2μM.