ACE2 over-expression/A549 cell line
|Human Angiotensin converting enzyme 2 (ACE2), also known as ACEH, is an integral membrane protein found on the surface of cells in the lungs, arteries, heart, kidney, and intestines.|
ACE2 serves as the entry point into cells for some coronaviruses, including the two strains that caused outbreaks of Severe acute respiratory syndrome (SARS-CoV) and coronavirus disease 2019 (COVID-19) (SARS-CoV-2).
|Stability:||32 passages(in-house test, that not means the cell line will be instable beyond the passages we tested.)|
|Synonym(s):||Angiotensin converting enzyme 2, ACEH, SARS-CoV, Coronavirus, COVID-19, SARS-CoV-2, ACE2 cells, ACE2 cell assay, covid19|
|Freeze Medium:||90% FBS+10% DMSO|
|Application(s):||Antibody Neutralizing Assay with 2019-nCov-S Pseudovirus|
|IV. Description of Host Cell Line|
|Organism:||Homo sapiens, human|
|Morphology:||Epithelial cells, growing adherently as monolayer|
|Ⅴ. Representative Data|
Figure 1. Recombinant A549 cell constitutively expressing full length human ACE2 (Genbank NM_021804.3).